FITC标记的组织胺H4受体抗体
产品名称： FITC标记的组织胺H4受体抗体
英文名称： Anti-HRH4/FITC
产品编号： HZ-10993R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-HRH4/FITC Conjugated antibody
FITC标记的组织胺H4受体抗体
| 英文名称 | Anti-HRH4/FITC |
| 中文名称 | FITC标记的组织胺H4受体抗体 |
| 别 名 | GPCR105; GPRv53; H4 antibody H4R; HH4R; Histamine H4 receptor; AXOR35; BG26; G protein coupled receptor 105; HRH4_HUMAN; SP9144. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 免疫学 信号转导 细胞凋亡 转录调节因子 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Mouse, Rat, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 44kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from mouse HRH4 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by a family of histamine receptors, which are a subset of the G-protein coupled receptor superfamily. This gene encodes a histamine receptor that is predominantly expressed in haematopoietic cells. The protein is thought to play a role in inflammation and allergy reponses. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009] Function: The H4 subclass of histamine receptors could mediate the histamine signals in peripheral tissues. Displays a significant level of constitutive activity (spontaneous activity in the absence of agonist) Subcellular Location: Cell membrane; Multi-pass membrane protein. Tissue Specificity: Expressed primarily in the bone marrow and eosinophils. Shows preferential distribution in cells of immunological relevance such as T-cells, dendritic cells, monocytes, mast cells, neutrophils. Also expressed in a wide variety of peripheral tissues, including the heart, kidney, liver, lung, pancreas, skeletal muscle, prostate, small intestine, spleen, testis, colon, fetal liver and lymph node. Similarity: Belongs to the G-protein coupled receptor 1 family. Database links: Entrez Gene: 59340 Human Entrez Gene: 225192 Mouse Entrez Gene: 170704 Rat Omim: 606792 Human SwissProt: Q9H3N8 Human SwissProt: Q91ZY2 Mouse SwissProt: Q91ZY1 Rat Unigene: 287388 Human Unigene: 207073 Mouse Unigene: 162272 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
Histamine是从肥大细胞、肠嗜铬样细胞和神经元释放出来的普遍存在的信使分子。它的各种作用是由一组组胺受体介导的，组胺受体是G蛋白偶联受体超家族的一个子集。该基因编码主要在造血细胞中表达的组胺受体。这种蛋白质被认为在炎症和过敏反应中起作用。该基因已发现编码不同亚型的多个转录变体。[ RefSeq，2009年5月提供]