PDE1A抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
PDE1A抗体

PDE1A抗体

商家询价

产品名称： PDE1A抗体

英文名称： PDE1AAntibody

产品编号： XY12442-2-

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

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 PDE1A抗体Applications

In-house applications ELISA, WB, IHC, IP     Application not tested? Please see our Guarantee.
Species specificity Human, Mouse; other species not tested.
Images
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  • 12442-2-AP;human brain tissuehuman brain tissue were subjected to SDS PAGE followed by western blot with 12442-2-AP(PDE1A antibody) at dilution of 1:500
  • 12442-2-AP;human gliomasImmunohistochemical of paraffin-embedded human gliomas using 12442-2-AP(PDE1A antibody) at dilution of 1:50 (under 10x lens)
  • 12442-2-AP;mouse brain tissueIP Result of anti-PDE1A (IP:12442-2-AP, 4ug; Detection:12442-2-AP 1:500) with mouse brain tissue lysate 4000ug.
Positive WB detected in Human brain tissue, mouse brain tissue
Positive IP detected in Mouse brain tissue
Positive IHC detected in Human gliomas tissue, mouse brain tissue
Recommended dilution WB : 1:500-1:5000
IP : 1:200-1:2000
IHC : 1:20-1:200
 PDE1A抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information PDE1A抗体
Immunogen PDE1A fusion protein ag3157 Full name Phosphodiesterase 1A, calmodulin-dependent
Calculated molecular
weight		 545aa,61 kDa Observed molecular 
weight		 61 kDa
GenBank accession 
number		 BC022480 Gene ID (NCBI) 5136
Gene symbol PDE1A Synonyms 61 kDa Cam PDE, Cam PDE 1A, hCam 1, HCAM1, HSPDE1A, PDE1A
Background

PDE1A(Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A) is also named as Cam-PDE 1A, 61 kDa Cam-PDE, hCam-1 and belongs to the cyclic nucleotide phosphodiesterase (PDEs) family. The PDEs play a role in signal transduction by regulating intracellular cyclic nucleotide concentrations through hydrolysis of cAMP and/or cGMP to their respective nucleoside 5-prime monophosphates. This protein has 9 isoforms produced by alternative splicing with the molecular weight from 57 kDa to 63 kDa. There is a report showing the major 67-kD PDE1A isoform identified in human sperm associates tightly with calmodulin and is not activated by Ca(2+)/calmodulin(PMID:12135876). PDE1A抗体

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