FITC标记的味觉受体蛋白家族2亚基50抗体
产品名称： FITC标记的味觉受体蛋白家族2亚基50抗体
英文名称： Anti-T2R50/FITC
产品编号： HZ-11617R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-T2R50/FITC Conjugated antibody
FITC标记的味觉受体蛋白家族2亚基50抗体
| 产品编号 | bs-11617R-FITC |
| 英文名称 | Anti-T2R50/FITC |
| 中文名称 | FITC标记的味觉受体蛋白家族2亚基50抗体 |
| 别 名 | T2R50; T2R50_HUMAN; T2R51; TAS2R50; Taste receptor type 2 member 50; Taste receptor type 2 member 51. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 神经生物学 信号转导 细胞膜受体 G蛋白偶联受体 G蛋白信号 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 35kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human GPCR TAS1R3 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: The sense of taste is essential for the survival of organisms. For example, the ability to identify sweet-tasting foods enables animals to seek out food with high nutritive value, whereas the ability to identify bitter substances enables them to avoid the ingestion of potentially harmful substances. A family of integral membrane proteins are involved in taste perception and include T1R, which is involved in sweet taste perception and T2R, which is involved in bitter taste perception. Both types of taste receptors couple to various G proteins to initiate signal transduction cascades. Specifically, T2R50 is expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells. Function: Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5. Subcellular Location: Cell membrane.Multi-pass membrane protein. Tissue Specificity: Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells. Similarity: Belongs to the G-protein coupled receptor T2R family. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
味觉对于生物的生存是必不可少的。例如，识别甜味食物的能力使动物能够寻找具有高营养价值的食物，而识别苦味物质的能力使他们能够避免摄入潜在有害物质。一系列完整的膜蛋白参与味觉感知，包括T1R，这涉及甜味感知和T2R，这涉及到苦味感知。这两种类型的味觉受体耦合到各种G蛋白，以启动信号转导级联。具体而言，T2R50在舌味觉受体细胞的亚群中表达，并且仅在胃泌素阳性细胞中表达。