APOB polyclonal antibody (HRP)
产品名称: APOB polyclonal antibody (HRP)
英文名称: APOB polyclonal antibody (HRP)
产品编号: PAB14374
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Goat polyclonal antibody raised against native APOB.
- Immunogen:
- Native purified human APOB.
- Host:
- Goat
- Reactivity:
- Human
- Specificity:
- This antibody can be used for detection of human APOB-48/100 in plasma and lipoproteins.
- Form:
- Liquid
- Conjugation:
- HRP
- Storage Buffer:
- In 50 mM PBS, 100 mM NaCl, pH 7.4 (10 mg/mL BSA, 0.01% thimerosal)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:100-1:4000)
Western Blot (1:100-1:4000)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains thimerosal: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Application Image
- Western Blot
- ELISA
- Entrez GeneID:
- 338
- Gene Name:
- APOB
- Gene Alias:
- FLDB
- Gene Description:
- apolipoprotein B (including Ag(x) antigen)
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms, apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination. Mutations in this gene or its regulatory region cause hypobetalipoproteinemia, normotriglyceridemic hypobetalipoproteinemia, and hypercholesterolemia due to ligand-defective apoB, diseases affecting plasma cholesterol and apoB levels. [provided by RefSeq
- Other Designations:
- OTTHUMP00000115994,apoB-100,apoB-48,apolipoprotein B,apolipoprotein B48
- Related Disease
- Abortion, Habitual
- Acute Disease
- Altitude Sickness
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- Alzheimer disease
- Amyotrophic Lateral Sclerosis
- Amyotrophic lateral sclerosis
- Anemia, Sickle Cell
- Angina Pectoris
- Aortic Valve Stenosis
- Arteriosclerosis
- Asthenozoospermia
- Atherosclerosis
- Atherosclerosis
- Azoospermia
- beta-Thalassemia
- Biliary Tract Neoplasms
- Blood Coagulation Disorders, Inherited
- Body Weight