SOD1 monoclonal antibody, clone 72B1
产品名称: SOD1 monoclonal antibody, clone 72B1
英文名称: SOD1 monoclonal antibody, clone 72B1
产品编号: MAB0684
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against full length recombinant SOD1.
- Immunogen:
- Recombinant protein corresponding to full length human SOD1.
- Host:
- Mouse
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Ammonium sulfate precipitation
- Concentration:
- 1 mg/mL
- Isotype:
- IgG1, kappa
- Storage Buffer:
- In HEPES, 150 mM NaCl (50% glycerol, 0.01% BSA, 0.03% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Immunoprecipitation (1-2 ul)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- The structure of holo and metal-deficient wild-type human Cu, Zn superoxide dismutase and its relevance to familial amyotrophic lateral sclerosis.
Strange RW, Antonyuk S, Hough MA, Doucette PA, Rodriguez JA, Hart PJ, Hayward LJ, Valentine JS, Hasnain SS.J Mol Biol. 2003 May 9;328(4):877-91.
- 2.
- Suppression of manganese superoxide dismutase augments sensitivity to radiation, hyperthermia and doxorubicin in colon cancer cell lines by inducing apoptosis.
Kuninaka S, Ichinose Y, Koja K, Toh Y.Br J Cancer. 2000 Oct;83(7):928-34.
- 3.
- Superoxide dismutase. Organelle specificity.
Weisiger RA, Fridovich I.J Biol Chem. 1973 May 25;248(10):3582-92.
- Entrez GeneID:
- 6647
- Gene Name:
- SOD1
- Gene Alias:
- ALS,ALS1,IPOA,SOD,homodimer
- Gene Description:
- superoxide dismutase 1, soluble
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene. [provided by RefSeq
- Other Designations:
- Cu /Zn superoxide dismutase,Cu/Zn superoxide dismutase,SOD, soluble,indophenoloxidase A,superoxide dismutase, cystolic
- Related Disease
- Acute Disease
- Albuminuria
- Alzheimer Disease
- Alzheimer disease
- Amyotrophic Lateral Sclerosis
- Amyotrophic lateral sclerosis
- Auditory Threshold
- Barrett Esophagus
- Birth Weight
- Brain Neoplasms
- Breast cancer
- Breast Neoplasms
- Carcinoma, Ductal, Breast
- Carcinoma, Lobular
- Cardiovascular Diseases
- Chronic Disease
- Cognition
- Cognition Disorders
- Coronary Artery Disease