HOXB7 monoclonal antibody (M01), clone 4F9
产品名称： HOXB7 monoclonal antibody (M01), clone 4F9
英文名称： HOXB7 monoclonal antibody (M01), clone 4F9
产品编号： H00003217-M01
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against a partial recombinant HOXB7.
- Immunogen:
- HOXB7 (NP_004493, 55 a.a. ~ 120 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Sequence:
- MQGLYPGGGGMAGQSAAGVYAAGYGLEPSSFNMHCAPFEQNLSGVCPGDSAKAAGAKEQRDSDLAA
- Host:
- Mouse
- Reactivity:
- Human
- Isotype:
- IgG1 Kappa
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (33 KDa) .
- MSDS:
Download
- Publication Reference
- 1.
- Evidence for a functional role of epigenetically regulated midcluster HOXB genes in the development of Barrett esophagus.
di Pietro M, Lao-Sirieix P, Boyle S, Cassidy A, Castillo D, Saadi A, Eskeland R, Fitzgerald RC.Proc Natl Acad Sci U S A. 2012 Jun 5;109(23):9077-82. Epub 2012 May 17.
- 2.
- Oncogenic HoxB7 requires TALE cofactors and is inactivated by a dominant-negative Pbx1 mutant in a cell-specific manner.
Fernandez LC, Errico MC, Bottero L, Penkov D, Resnati M, Blasi F, Care A.Cancer Lett. 2008 Aug 8;266(2):144-55. Epub 2008 Apr 2.
- Applications
- Western Blot (Transfected lysate)
- Western Blot analysis of HOXB7 expression in transfected 293T cell line by HOXB7 monoclonal antibody (M01), clone 4F9.
Lane 1: HOXB7 transfected lysate(23.97 KDa).
Lane 2: Non-transfected lysate. - Protocol Download
- Western Blot (Recombinant protein)
- Protocol Download
- Sandwich ELISA (Recombinant protein)
- Detection limit for recombinant GST tagged HOXB7 is approximately 0.3ng/ml as a capture antibody.
- Protocol Download
- Entrez GeneID:
- 3217
- GeneBank Accession#:
- NM_004502
- Protein Accession#:
- NP_004493
- Gene Name:
- HOXB7
- Gene Alias:
- HHO.C1,HOX2,HOX2C,Hox-2.3
- Gene Description:
- homeobox B7
- Omim ID:
- 142962
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene is a member of the Antp homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded nuclear protein functions as a sequence-specific transcription factor that is involved in cell proliferation and differentiation. Increased expression of this gene is associated with some cases of melanoma and ovarian carcinoma. [provided by RefSeq
- Other Designations:
- homeo box 2C,homeo box B7,homeo box c1 protein
- Related Disease